The error is telling you exactly what is wrong. You're attempting to connect to an SMTP server. Those are mail servers. Don't do that.
Error updating
I have this error when updating"Service not available, closing transmission channel. The server response was: Cannot connect to SMTP server 160.153.16.46 (160.153.16.46:25), connect error 10060"
Sorry, I thought was something related to wyUpdate. It was not the problem. Thank you!