What does the guid do?

In the demo video, when using the autoupdater control it says to set a guid which i have done

Do i need to know what this is for? Do i need to change it when i do a new release?

The GUID is a value that the AutomaticUpdater uses to distinguish your application from all the other apps using the AutomaticUpdater. Namely, it's used when caching updates.

Do i need to change it when i do a new release?

No.