The client.wyc file might be the cause of the problem, but only if the version embedded in the client.wyc file doesn't match the version of your app.
Otherwise the problem is caused by a file not being patched properly. You can debug this by unchecking the "Create a catch-all update for corrupt installations" in "File->Properties->Update & Server files".
Then rebuild your updates, and test again. If it fails to patch again it will list the file.
Tell me if this helps.